At least six people, including a 10-year-old girl and her mother, have lost their lives in a Russian missile strike on the Ukrainian city of Kryvyi Rih.
The attack, which took place early on Monday, also left 75 others injured, including 25 children, when the missiles slammed into a residential high-rise building.
Kryvyi Rih, the home city of President Volodymyr Zelensky, has become a recurrent target for Russian strikes.
In June, another devastating "massive missile attack" claimed 11 lives and injured 28 others in the city.
The latest assault saw dozens of people hospitalized, with some as young as four years old and others up to 17 years old.
President Zelensky, who spent his childhood in Kryvyi Rih, expressed his grief and posted a video showing the destruction caused by the missile strike.
As rescue operations were underway, more than 350 people were involved in the efforts, and around 150 individuals managed to escape the blast unharmed.
President Zelensky vowed that such acts of terror would not break their resolve.
In response to the rising attacks on civilian targets, Mykhailo Podolyak, a top adviser to President Zelensky, accused Moscow of launching "genocidal" attacks on Ukrainians and called for stronger measures to protect the country's airspace.
Russia has consistently denied deliberately targeting civilians, but Western leaders, including US President Joe Biden, have accused Russia of frequently attacking areas with no military significance.
The United Nations reported over 25,671 civilian casualties since Russia's invasion of Ukraine last year, though the true figure is feared to be much higher.
As tensions continue to escalate, violence has spread to other regions. In the southern city of Kherson, a 60-year-old utility worker lost his life in a rocket attack, and four others were injured.
A drone attack was also reported in Russia's border region of Bryansk, with a police station being targeted, according to Governor Alexander Bogomaz.
In response to these attacks, President Zelensky warned that war was coming back to Russia, and that assaults on Russian territory were an "inevitable, natural, and absolutely fair process" of the ongoing conflict between the two countries.
Regional governor Serhiy Lysak declared a day of mourning for the lives lost in the missile strike on Kryvyi Rih, and he pledged that Russia would be held accountable for the suffering of the Ukrainian people and every innocent life taken.